BDBM50602670 CHEMBL5178814

SMILES CNC(=O)[C@@]12C[C@@H]1[C@H]([C@H](O)[C@@H]2O)n1cnc2c(NCCc3ccc(OC)c(O)c3)nc(OCC3CC3)nc12

InChI Key InChIKey=MJPMZHWMGJXXMQ-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50602670   

TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandPNGBDBM50602670(CHEMBL5178814)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human adenosine A3A receptor stably expressed in HEK293 cells assessed as beta arrestin 2 recruitment potency by luciferase based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandPNGBDBM50602670(CHEMBL5178814)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human adenosine A3A receptor stably expressed in HEK293 cells assessed as mini G-alpha recruitment potency by luciferase based Na...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandPNGBDBM50602670(CHEMBL5178814)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I] N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human A3A receptor stably expressed in HEK293 cell membrane by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandPNGBDBM50602670(CHEMBL5178814)
Affinity DataKi:  12nMAssay Description:Displacement of [125I] N6-4-amino-3-iodobenzyl adenosine 5-N-methyluronamide from mouse A3A receptor stably expressed in HEK293 cell membrane by radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAdenosine receptor A1(Mouse)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandPNGBDBM50602670(CHEMBL5178814)
Affinity DataKi:  151nMAssay Description:Displacement of [3H] N6-R-phenylisopropyladenosine from mouse A1A receptor stably expressed in HEK293 cell membrane by radioligand inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Disease

Curated by ChEMBL
LigandPNGBDBM50602670(CHEMBL5178814)
Affinity DataKi:  4.72E+3nMAssay Description:Displacement of [3H]-2-p-2-(carboxyethyl)phenyl-ethylamino-5'-N-ethylcarboxamidoadenosine from human A2A receptor stably expressed in HEK293 cell mem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed