BDBM50602483 CHEMBL5175648

SMILES COc1cc(OC)cc(\C=C\c2ccc(OCCCCCCC(=O)NO)cc2)c1

InChI Key InChIKey=BKAQLWBLTMZOOO-UHFFFAOYSA-N

Data  3 IC50  1 Kd  1 Koff

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50602483   

TargetHistone deacetylase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602483(CHEMBL5175648)
Affinity DataIC50: 23nMAssay Description:Inhibition of HDAC in human MDA-MB-231 cells incubated for 24 hrs by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602483(CHEMBL5175648)
Affinity DataIC50: 683nMAssay Description:Inhibition of recombinant human HDAC1 using RHKK(Ac)AMC fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602483(CHEMBL5175648)
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant human HDAC6 using RHKK(Ac)AMC fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602483(CHEMBL5175648)
Affinity DataKd:  34nMAssay Description:Binding affinity to recombinant GST tagged STAT3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602483(CHEMBL5175648)
Affinity DataKon:  0.0152M-1s-1Assay Description:Binding affinity to recombinant GST tagged STAT3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed