BDBM50602480 CHEMBL5170981::US20240083885, Compound Jun9-5-4

SMILES C[C@H](NC(=O)C(N(C(=O)c1ccco1)c1ccc(OC(C)(C)C)cc1)c1cccnc1)c1ccccc1

InChI Key InChIKey=QVUDAPUVFJLICX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50602480   

TargetReplicase polyprotein 1ab(2019-nCoV)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50602480(CHEMBL5170981 | US20240083885, Compound Jun9-5-4)
Affinity DataIC50: 2.19E+4nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandPNGBDBM50602480(CHEMBL5170981 | US20240083885, Compound Jun9-5-4)
Affinity DataIC50: 21.9nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
Go to US Patent