BDBM50602402 CHEMBL5181099

SMILES CCCC1CNCc2c1[nH]c(=O)c(C#N)c2N1CCC2(COC2)CC1

InChI Key InChIKey=JJIRYGCNXYXJGY-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50602402   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Bayer

Curated by ChEMBL

LigandBDBM50602402(CHEMBL5181099)Copy SMILESCopy InChI

Affinity DataIC50: 6nMAssay Description:Inhibition of full length human PDE9A expressed in Sf9 insect cells using [3H]-cGMP as substrate incubated for 60 mins by microbeta scintillation cou...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/24/2023
Entry Details
Copy Entry DOIPubMed
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TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Mouse)
Bayer

Curated by ChEMBL

LigandBDBM50602402(CHEMBL5181099)Copy SMILESCopy InChI

Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of mouse PDE9A expressed in recombinant CHO cells coexpressing soluble guanylate cyclase incubated for 6 mins by [3H]-cGMP scintillation p...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/24/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL