BDBM50602371 CHEMBL5202255

SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(nc1)C(F)(F)F)C2)C(C)C

InChI Key InChIKey=SSCSXGXGTCGKOK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50602371   

TargetType II NADH:quinone oxidoreductase Ndh(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50602371(CHEMBL5202255)
Affinity DataIC50: 32nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant type II NADH dehydrogenase ndh expressed in Escherichia coli assessed as rate of NADH oxidation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetType II NADH:quinone oxidoreductase Ndh(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50602371(CHEMBL5202255)
Affinity DataIC50: 88nMAssay Description:Inhibition of Mycobacterium smegmatis MC2 155 recombinant type II NADH dehydrogenase ndh expressed in Escherichia coli assessed as rate of NADH oxida...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetType II NADH:quinone oxidoreductase NdhA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50602371(CHEMBL5202255)
Affinity DataIC50: 330nMAssay Description:Inhibition of Mycobacterium smegmatis MC2 155 recombinant ndhA assessed as rate of NADH oxidation in the presence of an electron acceptor menadioneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed