BDBM50602364 CHEMBL5204018

SMILES Cc1nc2cc(NC(=O)CCOCCOCCOCCOCCNC(=O)CNc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)ccc2n1Cc1ccc(cc1F)C(=O)NO

InChI Key InChIKey=HDFOPMODUYSQGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50602364   

TargetHistone deacetylase 6(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50602364(CHEMBL5204018)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC6 (1 to 1215 residues) using Z-Lys(Ac)-AMC as substrate preincubated for 90 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50602364(CHEMBL5204018)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of recombinant full length C-terminal His/Flag-tagged human HDAC1 (1 to 482 residues) using Z-Lys(Ac)-AMC as substrate preincubated for 90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed