BDBM50602229 CHEMBL5181688

SMILES COc1cc(OC)cc(c1)N(CCNC(C)C)c1ccc2ncc(nc2c1)-c1cnn(CCOc2ccc(cc2)C(=O)NO)c1

InChI Key InChIKey=PRXXXHCKGRNFLJ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50602229   

TargetHistone deacetylase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602229(CHEMBL5181688)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602229(CHEMBL5181688)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602229(CHEMBL5181688)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602229(CHEMBL5181688)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602229(CHEMBL5181688)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602229(CHEMBL5181688)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602229(CHEMBL5181688)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602229(CHEMBL5181688)
Affinity DataIC50: 288nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed