BDBM50602043 CHEMBL5179279

SMILES [H][C@]12CN(c3ccc(nc3)C(=O)NC)[C@]([H])(CN1Cc1cnc3cc(CC)c(=O)[nH]c3c1)C2

InChI Key InChIKey=CEJMJSUDCBTVDD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50602043   

TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602043(CHEMBL5179279)
Affinity DataIC50: 40nMAssay Description:Inhibition of PARP-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602043(CHEMBL5179279)
Affinity DataIC50: 340nMAssay Description:Inhibition of PARP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602043(CHEMBL5179279)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PARP-1 (unknown origin) binding to DNA assessed as DNA trapping activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602043(CHEMBL5179279)
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibition of PARP-2 (unknown origin) binding to DNA assessed as DNA trapping activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed