BDBM50601886 CHEMBL5171780

SMILES Cc1c(Cc2ccccc2)c(=O)oc2cc(OCC(=O)NC(CSCc3ccccc3)C(O)=O)ccc12

InChI Key InChIKey=XDWFPOZICRATHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50601886   

TargetSodium/bile acid cotransporter(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601886(CHEMBL5171780)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of TAMRA-labeled preS1-peptide binding to human NTCP in HepG2-hNTCP cells incubated for 30 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/bile acid cotransporter(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601886(CHEMBL5171780)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human NTCP mediated TCA uptake in HepG2-hNTCP cells incubated for 15 mins using [3H] taurocholic acid as substrate by liquid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed