BDBM50601811 CHEMBL5189627

SMILES CCCC1CCCCN1C(=O)c1cccc(c1)-c1cccc(c1)-n1ncc(C(O)=O)c1C1CC1c1ccccn1

InChI Key InChIKey=VSWIDSDLNMOACS-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50601811   

TargetKelch-like ECH-associated protein 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50601811(CHEMBL5189627)
Affinity DataIC50: 42nMAssay Description:Inhibition of 5'-TAMRA tagged NRF2 (unknown origin)/human recombinant N-terminal Avi tagged KEAP-1 (321 to 609 residues) expressed in Baculovirus sys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50601811(CHEMBL5189627)
Affinity DataEC50:  3.80E+3nMAssay Description:Induction of Nrf2 in human BEAS-2B cells assessed as increase in NQO1 protein level incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed