BDBM50601764 CHEMBL5201128

SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O

InChI Key InChIKey=ADFZKKWKESWUFY-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50601764   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601764(CHEMBL5201128)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of RET (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601764(CHEMBL5201128)
Affinity DataIC50: 22nMAssay Description:Inhibition of VEGFR1 (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601764(CHEMBL5201128)
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGFR2 (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601764(CHEMBL5201128)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of VEGFR3 (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601764(CHEMBL5201128)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of EGFR (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601764(CHEMBL5201128)
Affinity DataIC50: 51nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601764(CHEMBL5201128)
Affinity DataIC50: 39nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601764(CHEMBL5201128)
Affinity DataIC50: 46nMAssay Description:Inhibition of FGFR1 (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601764(CHEMBL5201128)
Affinity DataIC50: 100nMAssay Description:Inhibition of c-kit (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed