BDBM50601759 CHEMBL5175809::US11773078, Example 298

SMILES C[C@@H](O)CN1CCN(CC1)c1ncc(Oc2cc(CN3CCC(CC(O)=O)CC3)cc(n2)-c2cc(Cl)cc(Cl)c2)cn1

InChI Key InChIKey=BUVTTYFXRWVEJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50601759   

TargetFurin [108-574](Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM50601759(CHEMBL5175809 | US11773078, Example 298)
Affinity DataIC50: 0.631nMAssay Description:Reactions were performed in black 384-well polystyrene low volume plates (Greiner). Furin (108-574-Tev-Flag-His) enzyme was expressed and purified fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2023
Entry Details
Go to US Patent

TargetFurin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50601759(CHEMBL5175809 | US11773078, Example 298)
Affinity DataIC50: 0.631nMAssay Description:Inhibition of Tev-FLAG-His-tagged furin (108 to 574 residues) (unknown origin) using FAM-QRVRRAVGIDK-TAMRA as substrate and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed