BDBM50601603 CHEMBL5206949

SMILES C[C@H]1CC[C@H](N1c1ncnc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1cccc(F)c1

InChI Key InChIKey=PWZGSTGYDFNVFE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50601603   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50601603(CHEMBL5206949)
Affinity DataIC50: 3nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50601603(CHEMBL5206949)
Affinity DataIC50: 199nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50601603(CHEMBL5206949)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50601603(CHEMBL5206949)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed