BDBM50601542 CHEMBL5169576

SMILES CNc1ncc2cc(-c3ccc(cc3Cl)-c3nc(C)ccc3OC)c(=O)n(C[C@H]3OC[C@H](N)CO3)c2n1

InChI Key InChIKey=SPYPSRDGJWPJCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50601542   

TargetSerine/threonine-protein kinase SIK2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50601542(CHEMBL5169576)
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK2 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50601542(CHEMBL5169576)
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed