BDBM50601468 CHEMBL5179024

SMILES CCOC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)C(=O)c1c([nH]c2ccc(cc12)N=C=S)-c1ccccc1

InChI Key InChIKey=BDYNTWOCTIWVBG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50601468   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50601468(CHEMBL5179024)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of MDM2 in human U-87 MG cells incubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50601468(CHEMBL5179024)
Affinity DataKi:  108nMAssay Description:Displacement of [3H] PK11195 from TSPO in human U-87 MGcell membrane assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed