BDBM50601442 CHEMBL5173625

SMILES CCN(CC)CCN1Cc2[nH]c(\C=C3/C(=O)Nc4ccc(Br)cc34)c(C)c2C1=O

InChI Key InChIKey=GKTNIBQDODXGKX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50601442   

TargetVascular endothelial growth factor receptor 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50601442(CHEMBL5173625)
Affinity DataIC50: 25nMAssay Description:Inhibition of VEGFR-2 (unknown origin) preincubated for 20 mins followed 33P ATP addition and measured after 120 min by hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50601442(CHEMBL5173625)
Affinity DataIC50: 16nMAssay Description:Inhibition of PDGFR-beta (unknown origin) preincubated for 20 mins followed 33P ATP addition and measured after 120 min by hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50601442(CHEMBL5173625)
Affinity DataIC50: 179nMAssay Description:Inhibition of VEGFR-2 (unknown origin) induced tube formation in HUVECs cocultured with fibroblasts measured after 11 days with media renewing every ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed