BDBM50601429 CHEMBL492807

SMILES COc1cc(\C=C\c2cc(\C=C\c3ccc(O)c(OC)c3)n(C)n2)ccc1O

InChI Key InChIKey=FFBTZOAEBAETTQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50601429   

TargetAmyloid-beta precursor protein(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601429(CHEMBL492807)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601429(CHEMBL492807)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601429(CHEMBL492807)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of tau (unknown origin) transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed