BDBM50601423 CHEMBL5195740

SMILES COc1cc(\C=C\c2cc(\C=C\c3ccc(OCC(O)=O)c(OC)c3)on2)ccc1OCC(O)=O

InChI Key InChIKey=ARBLYNSLBGFYKG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50601423   

TargetAmyloid-beta precursor protein(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601423(CHEMBL5195740)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of amyloid beta 42 transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601423(CHEMBL5195740)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601423(CHEMBL5195740)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601423(CHEMBL5195740)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of tau (unknown origin) transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed