BDBM50601383 CHEMBL5177286

SMILES CNc1ncnc2c(C)[nH]nc12

InChI Key InChIKey=SUUWWTXOJILAMU-UHFFFAOYSA-N

Data  6 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50601383   

TargetYTH domain-containing family protein 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601383(CHEMBL5177286)
Affinity DataIC50: 4.10E+5nMAssay Description:Binding affinity to GST-tagged YTHDF2 m6A-reader domain (unknown origin) using RRACH-containing methylated oligoRNA incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetYTH domain-containing protein 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601383(CHEMBL5177286)
Affinity DataIC50: 3.90E+4nMAssay Description:Binding affinity to GST-tagged YTHDC1 m6A-reader domain (unknown origin) using RRACH-containing methylated oligoRNA incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetYTH domain-containing family protein 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601383(CHEMBL5177286)
Affinity DataIC50: 1.74E+5nMAssay Description:Inhibition of YTHDF2 YTH domain (unknown origin) (383 to 579 residues) expressed as Escherichia coli BL21 (DE3) Rosetta cells by HTFR based binding a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetYTH domain-containing protein 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601383(CHEMBL5177286)
Affinity DataIC50: 3.90E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetYTH domain-containing protein 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601383(CHEMBL5177286)
Affinity DataKd:  1.68E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetYTH domain-containing protein 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601383(CHEMBL5177286)
Affinity DataKd:  1.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetYTH domain-containing protein 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601383(CHEMBL5177286)
Affinity DataIC50: 3.90E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetYTH domain-containing family protein 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50601383(CHEMBL5177286)
Affinity DataIC50: 4.10E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed