BDBM50601277 CHEMBL5183315

SMILES CC(C)OC(=O)Nc1ccc(cn1)C1=NN(C(C1C)c1ccccc1)C(=O)c1ccc(Br)cc1

InChI Key InChIKey=MAXZDUQMLSMNEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50601277   

TargetApoptosis regulator Bcl-2(Human)
University of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50601277(CHEMBL5183315)
Affinity DataIC50: 2nMAssay Description:Inhibition of biotin-linker-Beclin 1 BH3 peptide binding to human C-terminal 6His-tagged Bcl-2 (1 to 218 residues) expressed in Escherichia coli BL21...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50601277(CHEMBL5183315)
Affinity DataIC50: 157nMAssay Description:Inhibition of biotin-linker-Bax BH3 peptide binding to human C-terminal 6His-tagged Bcl-2 (1 to 218 residues) expressed in Escherichia coli BL21 Star...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed