BDBM50601225 CHEMBL5203319

SMILES Fc1ccccc1Cc1cc(=O)n2nc(Nc3c4CCCc4cc4CCCc34)nc2[nH]1

InChI Key InChIKey=DQKOGWMCAAXGOC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50601225   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Nodthera

Curated by ChEMBL

LigandBDBM50601225(CHEMBL5203319)Copy SMILESCopy InChI

Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-pretreated PBMC (unknown origin) assessed as reduction in IL-1beta release pretreated for 30 mins followed by...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/24/2023
Entry Details
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