BDBM50601224 CHEMBL5175650

SMILES Cc1ccccc1Cc1cc(=O)n2nc(Nc3c4CCCc4cc4CCCc34)nc2[nH]1

InChI Key InChIKey=NSFNAEJDADBITE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50601224   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Nodthera

Curated by ChEMBL

LigandBDBM50601224(CHEMBL5175650)Copy SMILESCopy InChI

Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-pretreated PBMC (unknown origin) assessed as reduction in IL-1beta release pretreated for 30 mins followed by...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/24/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL