BDBM50601211 CHEMBL5186834

SMILES O=c1cc(Cc2ccccc2)[nH]c2nc(Nc3c4CCCc4cc4CCCc34)nn12

InChI Key InChIKey=VBZWSSMQKISXSU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50601211   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Nodthera

Curated by ChEMBL

LigandBDBM50601211(CHEMBL5186834)Copy SMILESCopy InChI

Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-pretreated PBMC (unknown origin) assessed as reduction in IL-1beta release pretreated for 30 mins followed by...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/24/2023
Entry Details
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