BDBM50601117 CHEMBL5174517

SMILES OC(=O)c1ccc(CNc2nc3ccc(cc3o2)-c2nc(nc(n2)N2CCOCC2)N2CCOCC2)cc1

InChI Key InChIKey=AOSQGSGJTZNGRW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50601117   

LigandPNGBDBM50601117(CHEMBL5174517)
Affinity DataIC50: 6nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate in presence of ATP measured after 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50601117(CHEMBL5174517)
Affinity DataIC50: 100nMAssay Description:Inhibition of PI3Kbeta (unknown origin) in presence of [33P]-ATP incubated for 2 hrs by hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50601117(CHEMBL5174517)
Affinity DataIC50: 51nMAssay Description:Inhibition of PI3Kdelta (unknown origin) in presence of [33P]-ATP incubated for 2 hrs by hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50601117(CHEMBL5174517)
Affinity DataIC50: 3.49E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) in presence of [33P]-ATP incubated for 2 hrs by hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed