BDBM50601061 CHEMBL5169564

SMILES COc1cc2cnnc(N[C@H](C)c3cccc(c3)C(F)(F)F)c2cc1OC

InChI Key InChIKey=ILBDBWRMOHLKOZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50601061   

TargetEpidermal growth factor receptor(Human)
Mirati Therapeutics

Curated by ChEMBL
LigandPNGBDBM50601061(CHEMBL5169564)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR in presence of ATP by radiometric HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSon of sevenless homolog 1(Human)
Mirati Therapeutics

Curated by ChEMBL
LigandPNGBDBM50601061(CHEMBL5169564)
Affinity DataKi:  52nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed