BDBM50600763 CHEMBL5194112::US20240043470, Compound 1-56
SMILES FC(F)(F)CNC(=O)[C@@H]1Cc2cccc(Oc3cccc(C[C@H](N4CCCC4=O)C(=O)N[C@@H](CCc4ccccc4)C(=O)N1)c3)c2
InChI Key InChIKey=MNBPUBDMQBHNLF-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50600763
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5c subunit using Suc-LLVY-AMC as substrate measured after 1.2 hrs in presence of SDSMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Ac-ANW-AMC as substrate measured after 1.2 hrs in presence of SDSMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5c subunitMore data for this Ligand-Target Pair
Affinity DataIC50: 3.39E+4nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunitMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.39E+4nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair