BDBM50600358 CHEMBL5197315

SMILES CN1CCN(CC1)C(=O)COc1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1

InChI Key InChIKey=WYFVLMHLYJWYJP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50600358   

TargetSodium channel protein type 7 subunit alpha(Human)
Abbvie

Curated by ChEMBL

LigandBDBM50600358(CHEMBL5197315)Copy SMILESCopy InChI

Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human Nav 1.7 expressed in HEK293F cells incubated for 3 mins by FRET based membrane potential assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbvie

Curated by ChEMBL

LigandBDBM50600358(CHEMBL5197315)Copy SMILESCopy InChI

Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of hERG channel by electrophysiologyMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL