BDBM50600322 CHEMBL5172847

SMILES COc1cc(N2CCC3(CCN(C)CC3)CC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1

InChI Key InChIKey=XQEYPEQDMUAORO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50600322   

TargetALK tyrosine kinase receptor(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50600322(CHEMBL5172847)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of ALK C1156Y mutant (unknown origin) using biotinylated substrate incubated for 1 hr in the presence of ATP at Km concentration by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50600322(CHEMBL5172847)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) using biotinylated substrate incubated for 1 hr in the presence of ATP at Km concentration by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50600322(CHEMBL5172847)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of wild type ALK (unknown origin) using biotinylated substrate incubated for 1 hr in the presence of ATP at Km concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed