BDBM50600227 CHEMBL5187762

SMILES COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC(=O)N1CCN(C[C@H]1C)C(=O)C#C

InChI Key InChIKey=AVXVZHSZWMMNIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50600227   

TargetEpidermal growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50600227(CHEMBL5187762)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) expressed in Sf21 insect cells using kinase substrate 22 incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed