BDBM50600184 CHEMBL5182381

SMILES Cc1cc(ccc1F)S(=O)(=O)Nc2ccc3c(c2)CN(C(=O)N3)C

InChI Key InChIKey=UQXHNDHWFYISEE-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50600184   

TargetBromodomain-containing protein 4(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50600184(CHEMBL5182381)
Affinity DataIC50: 330nMAssay Description:Displacement of biotinylated acetylated histone H4 peptide from human recombinant N-terminal GST-tagged BRD4 BD1 (49 to 170 residues) expressed in Es...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Southern Research

Curated by ChEMBL
LigandPNGBDBM50600184(CHEMBL5182381)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human BRD4 BD1 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed