BDBM50600168 CHEMBL5171952

SMILES Cn1cc(Nc2ncc3ccc(=O)n(Cc4cccc(NC(=O)C=C)c4)c3n2)cn1

InChI Key InChIKey=RAQWADYTCVHNNZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50600168   

TargetTyrosine-protein kinase JAK3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50600168(CHEMBL5171952)
Affinity DataIC50: 1.80nMAssay Description:Covalent inhibition of recombinant recombinant human GST-tagged JAK3(781 to 1124 residues) expressed in baculovirus expression system incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed