BDBM50600164 CHEMBL5180842

SMILES COc1cc(ccc1Nc1ncc2ccc(=O)n(Cc3cccc(NC(=O)C=C)c3)c2n1)N1CCN(CC1)C(C)=O

InChI Key InChIKey=OKPSHIUYADZRMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50600164   

TargetTyrosine-protein kinase JAK3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50600164(CHEMBL5180842)
Affinity DataIC50: 3.30nMAssay Description:Covalent inhibition of recombinant recombinant human GST-tagged JAK3(781 to 1124 residues) expressed in baculovirus expression system incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed