BDBM50600117 CHEMBL5173568::US20240336588, Compound 63

SMILES Cc1c(O)c(O)ccc1C(=O)O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c1cc(O)c(O)c(O)c1

InChI Key InChIKey=AHUSIPYYYGNTQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50600117   

LigandPNGBDBM50600117(CHEMBL5173568 | US20240336588, Compound 63)
Affinity DataIC50: 553nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50600117(CHEMBL5173568 | US20240336588, Compound 63)
Affinity DataIC50: 100nMAssay Description:DYRK1A assay. Substrate, HT-PRD (Proline rich domain, residues 746-864 of dynamin 1a, prepared as N-terminal tagged 6×His fusion protein), was dilute...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent