BDBM50600112 CHEMBL5173930::US20240336588, Compound 42

SMILES Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)cc3O)[C@@H](Oc2c1)c1cc(O)c(O)c(O)c1

InChI Key InChIKey=YIQCEOVSTCMASU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50600112   

LigandPNGBDBM50600112(CHEMBL5173930 | US20240336588, Compound 42)
Affinity DataIC50: 172nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50600112(CHEMBL5173930 | US20240336588, Compound 42)
Affinity DataIC50: 100nMAssay Description:DYRK1A assay. Substrate, HT-PRD (Proline rich domain, residues 746-864 of dynamin 1a, prepared as N-terminal tagged 6×His fusion protein), was dilute...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent