BDBM50599964 CHEMBL5179059::US20250129073, Compound 49

SMILES Cn1ccc2ccc(cc12)C(=O)N1CCC2(CCN(Cc3cc(F)ccc3F)C2=O)CC1

InChI Key InChIKey=YATBYSZORSKSPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599964   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599964(CHEMBL5179059 | US20250129073, Compound 49)
Affinity DataIC50: 92nMAssay Description:Inhibition of human RIPK1 incubated for 40 min in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599964(CHEMBL5179059 | US20250129073, Compound 49)
Affinity DataIC50: 92nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent