BDBM50599900 CHEMBL5190788

SMILES Clc1cccc(N2CCN(CCCN3CCN(CC3)c3ncccc3C#N)CC2)c1Cl

InChI Key InChIKey=RTVQLAGHMGMPSS-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50599900   

Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599900(CHEMBL5190788)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599900(CHEMBL5190788)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599900(CHEMBL5190788)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599900(CHEMBL5190788)
Affinity DataKi:  470nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599900(CHEMBL5190788)
Affinity DataKi:  570nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed