BDBM50599878 CHEMBL5170381

SMILES Fc1ccc(COC2CCN(Cc3ccc4[nH]cnc4c3)CC2)cc1F

InChI Key InChIKey=NMWYMABDXNLKFE-UHFFFAOYSA-N

Data  9 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50599878   

TargetD(4) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599878(CHEMBL5170381)
Affinity DataIC50: 4.27E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK293 cell membrane by competitive inhibition based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599878(CHEMBL5170381)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H] Pentazocine from sigma 1 receptor in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599878(CHEMBL5170381)
Affinity DataKi:  12nMAssay Description:Binding affinity to sigma 1 receptor in human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599878(CHEMBL5170381)
Affinity DataKi:  166nMAssay Description:Displacement of [3H]DTG from sigma-2 receptor in HEK293 cell membrane assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599878(CHEMBL5170381)
Affinity DataKi:  4.08E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membrane by competitive inhibition based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599878(CHEMBL5170381)
Affinity DataKi:  4.08E+3nMAssay Description:Displacement of [3H]N-methylspiperone from D3 receptor in HEK293 cell membrane assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599878(CHEMBL5170381)
Affinity DataKi:  4.28E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK293 cell membrane by competitive inhibition based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599878(CHEMBL5170381)
Affinity DataKi:  4.28E+3nMAssay Description:Displacement of [3H]N-methylspiperone from D4 receptor in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(1B) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599878(CHEMBL5170381)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from D5 receptor in HEK293 cell membrane assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599878(CHEMBL5170381)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from D1 receptor in HEK293 cell membrane assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed