BDBM50599863 CHEMBL5174753

SMILES Cc1ccc(CO[C@H]2CCCN(Cc3ccc(cc3)C#N)C2)cc1

InChI Key InChIKey=PPZBZJPCFRFDCX-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50599863   

TargetD(4) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599863(CHEMBL5174753)
Affinity DataIC50: 1.02E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK293 cell membrane by competitive inhibition based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599863(CHEMBL5174753)
Affinity DataKi:  14nMAssay Description:Displacement of [3H] Pentazocine from sigma 1 receptor in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599863(CHEMBL5174753)
Affinity DataKi:  248nMAssay Description:Displacement of [3H]DTG from sigma-2 receptor in HEK293 cell membrane assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599863(CHEMBL5174753)
Affinity DataKi:  1.01E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK293 cell membrane by competitive inhibition based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599863(CHEMBL5174753)
Affinity DataKi:  1.01E+3nMAssay Description:Displacement of [3H]N-methylspiperone from D4 receptor in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599863(CHEMBL5174753)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from D1 receptor in HEK293 cell membrane assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed