BDBM50599801 CHEMBL5172348

SMILES CCN(C)C(=O)Oc1ccc(cc1)C1CC(=O)c2c(O)cc(OC(=O)N(C)CC)cc2O1

InChI Key InChIKey=KNWDCQYJQCVXHS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50599801   

TargetAcetylcholinesterase(Rat)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50599801(CHEMBL5172348)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine as substrate incubated for 15 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCarboxylic ester hydrolase(Rat)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50599801(CHEMBL5172348)
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of rat serum Butyrylcholine esterase using butyrylthiocholine as substrate incubated for 15 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50599801(CHEMBL5172348)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine as substrate incubated for 15 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50599801(CHEMBL5172348)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine as substrate incubated for 15 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed