BDBM50599763 CHEMBL5206364

SMILES Cc1cn(CCC#N)c(=O)c2cc(Cn3nc(cc3Cl)C(F)F)nn12

InChI Key InChIKey=XQRYJFBBEGHCDR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599763   

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599763(CHEMBL5206364)
Affinity DataEC50:  2.00E+3nMAssay Description:Positive allosteric modulator activity at GluN1a/GluN2A (unknown origin) expressed in CHO cells in presence of glutamate by Ca2+ influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599763(CHEMBL5206364)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed