BDBM50599755 CHEMBL5196482

SMILES CCN(Cc1cc2n(ccn(CCC#N)c2=O)n1)c1ccc(F)cc1

InChI Key InChIKey=SCCZJCOIRVYXNF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599755   

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599755(CHEMBL5196482)
Affinity DataEC50:  5.20E+3nMAssay Description:Positive allosteric modulator activity at GluN1a/GluN2A (unknown origin) expressed in CHO cells in presence of glutamate by Ca2+ influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599755(CHEMBL5196482)
Affinity DataIC50: 2.20E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed