BDBM50599749 CHEMBL5171984

SMILES FC(F)(F)c1cc(Cl)n(Cc2cc(=O)n3c([C@@H]4C[C@@H]4C#N)c(sc3n2)C(F)(F)F)n1

InChI Key InChIKey=FTIBNGABJNFFAI-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50599749   

TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599749(CHEMBL5171984)
Affinity DataEC50:  2.40E+4nMAssay Description:Positive allosteric modulator activity at GluA2-AMPA receptor (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599749(CHEMBL5171984)
Affinity DataIC50: 880nMAssay Description:Displacement of [3H]-HBT1 from GluA2-AMPA receptor (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599749(CHEMBL5171984)
Affinity DataEC50:  11nMAssay Description:Positive allosteric modulator activity at GluN2A receptor (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed