BDBM50599748 CHEMBL5202949

SMILES CCN(Cc1ccc(s1)C(=O)N1CCC[C@@H]1C#N)c1ccc(F)cc1

InChI Key InChIKey=AQYKGKLKIQVGOS-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50599748   

TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599748(CHEMBL5202949)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulator activity at GluA2-AMPA receptor (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599748(CHEMBL5202949)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]-HBT1 from GluA2-AMPA receptor (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599748(CHEMBL5202949)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulator activity at GluN2A receptor (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed