BDBM50599579 CHEMBL5170301

SMILES [H][C@@]12CC[C@@]3(O1)[C@@]1([H])Cc4ccc(O)cc4[C@@]3(CCN1CC1CC1)C[C@@H]2NC(=O)CCc1ccccc1

InChI Key InChIKey=FJCPWHQOXLNSHQ-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50599579   

TargetMu-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50599579(CHEMBL5170301)
Affinity DataEC50:  9.40nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 2 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50599579(CHEMBL5170301)
Affinity DataEC50:  55nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 2 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50599579(CHEMBL5170301)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 2 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50599579(CHEMBL5170301)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50599579(CHEMBL5170301)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50599579(CHEMBL5170301)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]-DPDPE from recombinant human DOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed