BDBM50599551 CHEMBL5207762

SMILES COc1cc2ccn(C\C=C\C(=O)Nc3ccccc3)c(=O)c2cc1OC

InChI Key InChIKey=JANOHAAHODFMQZ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50599551   

TargetProteasome subunit beta type-1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50599551(CHEMBL5207762)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of 20S immuno proteosome beta1i subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Glu-AMC as fluorogenic substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50599551(CHEMBL5207762)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of 20S immuno proteosome beta2i subunit (unknown origin) assessed as substrate hydrolysis using Boc-Leu-Arg-Arg-AMC as fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50599551(CHEMBL5207762)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of 20S constitutive proteosome beta2c subunit (unknown origin) assessed as substrate hydrolysis using Boc-Leu-Arg-Arg-AMC as fluorogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteasome subunit beta type-1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50599551(CHEMBL5207762)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of 20S constitutive proteosome beta1c subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Glu-AMC as fluorogenic sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteasome subunit beta type-5(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50599551(CHEMBL5207762)
Affinity DataKi:  4.90E+4nMAssay Description:Inhibition of 20S constitutive proteosome beta5c subunit (unknown origin) assessed as substrate hydrolysis using Suc-Leu-Leu-Val-Tyr-AMC as fluorogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed