BDBM50599384 CHEMBL5185564

SMILES c1[nH]c2ccccc2c1-c1ccc2n[se]nc2c1

InChI Key InChIKey=TWAZFNIRSNDUNZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50599384   

TargetTryptophan 2,3-dioxygenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50599384(CHEMBL5185564)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human TDO2 expressed in Escherichia coli BL21-DE3 rosetta cells at pH 6.5 potassium phosphate buffer using L-tryptophan as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50599384(CHEMBL5185564)
Affinity DataIC50: 94nMAssay Description:Inhibition of human TDO2 expressed in mouse P815B cells using L-tryptophan as substrate incubated for 7 hrs by UPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50599384(CHEMBL5185564)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human IDO1 in potassium phosphate buffer at pH 6.5 using L-tryptophan as substrate incubated for 8 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50599384(CHEMBL5185564)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human IDO1 expressed in mouse P815B cells using L-tryptophan as substrate incubated for 24 hrs by UPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed