BDBM50599210 CHEMBL5170316

SMILES Cc1c(oc2ncn(Cc3nnn(C[C@H](O)c4cc5ccccc5s4)n3)c(=O)c12)C(N)=O

InChI Key InChIKey=FKCJHLWKMWRKBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599210   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50599210(CHEMBL5170316)
Affinity DataIC50: 10nMAssay Description:Inhibition of human TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced intracellular calcium accumulation incubated for 10 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50599210(CHEMBL5170316)
Affinity DataIC50: 10nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
Go to US Patent