BDBM50599049 CHEMBL5202721

SMILES CCc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(c2)C#Cc2cnc3cccnn23)cc(c1)C(F)(F)F

InChI Key InChIKey=JSKADPJHPCAFPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599049   

TargetTyrosine-protein kinase ABL1(Human)
Oregon Health and Science University

Curated by ChEMBL
LigandPNGBDBM50599049(CHEMBL5202721)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Oregon Health and Science University

Curated by ChEMBL
LigandPNGBDBM50599049(CHEMBL5202721)
Affinity DataIC50: 149nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed