BDBM50599046 CHEMBL5171402

SMILES COc1ccc(cc1C#Cc1cnc2cccnn12)C(=O)Nc1ccc(CN2CCN(C)CC2)c(c1)C(F)(F)F

InChI Key InChIKey=RYGQVUMXCKBWTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599046   

TargetTyrosine-protein kinase ABL1(Human)
Oregon Health and Science University

Curated by ChEMBL
LigandPNGBDBM50599046(CHEMBL5171402)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Oregon Health and Science University

Curated by ChEMBL
LigandPNGBDBM50599046(CHEMBL5171402)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed