BDBM50599044 CHEMBL5178286

SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cn(C)cn3)cc2C(F)(F)F)CC1

InChI Key InChIKey=VQCMXFGNJGXFMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599044   

TargetTyrosine-protein kinase ABL1(Human)
Oregon Health and Science University

Curated by ChEMBL
LigandPNGBDBM50599044(CHEMBL5178286)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Oregon Health and Science University

Curated by ChEMBL
LigandPNGBDBM50599044(CHEMBL5178286)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed